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RNA localization in confined cells depends on cellular mechanical activity and contributes to confined migration

Cancer cells experience mechanical confining forces during metastasis and, consequently, can alter their migratory mechanisms. Localization of numerous mRNAs to cell protrusions contributes to cell polarization and migration and is controlled by proteins that can bind RNA and/or cytoskeletal element...

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Detalles Bibliográficos
Autores principales: Moriarty, Rebecca A., Mili, Stavroula, Stroka, Kimberly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850802/
https://www.ncbi.nlm.nih.gov/pubmed/35198898
http://dx.doi.org/10.1016/j.isci.2022.103845