Cargando…

Spotlight on alternative frame coding: Two long overlapping genes in Pseudomonas aeruginosa are translated and under purifying selection

The existence of overlapping genes (OLGs) with significant coding overlaps revolutionizes our understanding of genomic complexity. We report two exceptionally long (957 nt and 1536 nt), evolutionarily novel, translated antisense open reading frames (ORFs) embedded within annotated genes in the patho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kreitmeier, Michaela, Ardern, Zachary, Abele, Miriam, Ludwig, Christina, Scherer, Siegfried, Neuhaus, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850804/ https://www.ncbi.nlm.nih.gov/pubmed/35198897 http://dx.doi.org/10.1016/j.isci.2022.103844

Ejemplares similares

A Novel pH-Regulated, Unusual 603 bp Overlapping Protein Coding Gene pop Is Encoded Antisense to ompA in Escherichia coli O157:H7 (EHEC)
por: Zehentner, Barbara, et al.
Publicado: (2020)

The novel EHEC gene asa overlaps the TEGT transporter gene in antisense and is regulated by NaCl and growth phase
por: Vanderhaeghen, Sonja, et al.
Publicado: (2018)

Biological factors in the synthetic construction of overlapping genes
por: Wichmann, Stefan, et al.
Publicado: (2021)

Are Antisense Proteins in Prokaryotes Functional?
por: Ardern, Zachary, et al.
Publicado: (2020)

Analysis of antibacterial and antibiofilm activity of purified recombinant Azurin from Pseudomonas aeruginosa
por: Mohammadi-Barzelighi, Hajar, et al.
Publicado: (2019)

Predicting Statistical Properties of Open Reading Frames in Bacterial Genomes
por: Mir, Katharina, et al.
Publicado: (2012)

Transcriptome Dynamics of Pseudomonas aeruginosa during Transition from Overlapping To Non-Overlapping Cell Cycles
por: Alpers, Kathrin, et al.
Publicado: (2023)

The Novel Anaerobiosis-Responsive Overlapping Gene ano Is Overlapping Antisense to the Annotated Gene ECs2385 of Escherichia coli O157:H7 Sakai
por: Hücker, Sarah M., et al.
Publicado: (2018)

Spotlight on Zebrafish: Translational Impact
por: Patton, E. Elizabeth, et al.
Publicado: (2014)

Unified Workflow for the Rapid and In-Depth Characterization of Bacterial Proteomes
por: Abele, Miriam, et al.
Publicado: (2023)

Three Novel Antisense Overlapping Genes in E. coli O157:H7 EDL933
por: Graf, Franziska, et al.
Publicado: (2022)

Frame overlap Bragg edge imaging
por: Busi, Matteo, et al.
Publicado: (2020)

Evidence for the recent origin of a bacterial protein-coding, overlapping orphan gene by evolutionary overprinting
por: Fellner, Lea, et al.
Publicado: (2015)

OLGenie: Estimating Natural Selection to Predict Functional Overlapping Genes
por: Nelson, Chase W, et al.
Publicado: (2020)

Initiation at AUGUG and GUGUG sequences can lead to translation of overlapping reading frames in E. coli
por: Kohl, Maximilian P, et al.
Publicado: (2022)

A membrane‐bound esterase PA2949 from Pseudomonas aeruginosa is expressed and purified from Escherichia coli
por: Kovacic, Filip, et al.
Publicado: (2016)

Anti‐biofilm and anti‐virulence effects of silica oxide nanoparticle–conjugation of lectin purified from Pseudomonas aeruginosa
por: Nsayef Muslim, Sahira, et al.
Publicado: (2021)

Spotlight on zebrafish: the next wave of translational research
por: Patton, E. Elizabeth, et al.
Publicado: (2019)

Selective Constraint on the Upstream Open Reading Frames That Overlap with Coding Sequences in Animals
por: Hsu, Ming-Kung, et al.
Publicado: (2012)

Transcriptional analysis in bacteriophage Fc02 of Pseudomonas aeruginosa revealed two overlapping genes with exclusion activity
por: Ramírez-Sánchez, Irais, et al.
Publicado: (2023)

Proteomic profiling spotlights the molecular targets and the impact of the natural antivirulent umbelliferone on stress response, virulence factors, and the quorum sensing network of Pseudomonas aeruginosa
por: Kasthuri, Thirupathi, et al.
Publicado: (2022)

HexSE: Simulating evolution in overlapping reading frames
por: Muñoz-Baena, Laura, et al.
Publicado: (2023)

Dynamically evolving novel overlapping gene as a factor in the SARS-CoV-2 pandemic
por: Nelson, Chase W, et al.
Publicado: (2020)

Stabilization of Hfq-mediated translational repression by the co-repressor Crc in Pseudomonas aeruginosa
por: Malecka, Ewelina M, et al.
Publicado: (2021)

A novel short L-arginine responsive protein-coding gene (laoB) antiparallel overlapping to a CadC-like transcriptional regulator in Escherichia coli O157:H7 Sakai originated by overprinting
por: Hücker, Sarah M., et al.
Publicado: (2018)

Resistance of Pseudomonas Aeruginosa
por: Graevenitz, Alexander Von
Publicado: (1977)

Pseudomonas aeruginosa Biofilms
por: Thi, Minh Tam Tran, et al.
Publicado: (2020)

Low overlap between carbapenem resistant Pseudomonas aeruginosa genotypes isolated from hospitalized patients and wastewater treatment plants
por: Golle, Andrej, et al.
Publicado: (2017)

The prevalence of Pseudomonas aeruginosa and multidrug resistant Pseudomonas aeruginosa in healthy captive ophidian
por: Sala, Andrea, et al.
Publicado: (2019)

A purified and lyophilized Pseudomonas aeruginosa derived pyocyanin induces promising apoptotic and necrotic activities against MCF-7 human breast adenocarcinoma
por: Abdelaziz, Ahmed A., et al.
Publicado: (2022)

Spaceflight Promotes Biofilm Formation by Pseudomonas aeruginosa
por: Kim, Wooseong, et al.
Publicado: (2013)

Inactivation of Nitrite-Dependent Nitric Oxide Biosynthesis Is Responsible for Overlapped Antibiotic Resistance between Naturally and Artificially Evolved Pseudomonas aeruginosa
por: Kuang, Su-fang, et al.
Publicado: (2021)

Discovery of numerous novel small genes in the intergenic regions of the Escherichia coli O157:H7 Sakai genome
por: Hücker, Sarah M., et al.
Publicado: (2017)

Pseudomonas Aeruginosa: Resistance to the Max
por: Poole, Keith
Publicado: (2011)

Biotransformation of myrcene by Pseudomonas aeruginosa
por: Esmaeili, Akbar, et al.
Publicado: (2011)

Cefepime-Resistant Pseudomonas aeruginosa
por: Akhabue, Ehimare, et al.
Publicado: (2011)

The Regulatory Network of Pseudomonas aeruginosa
por: Galán-Vásquez, Edgardo, et al.
Publicado: (2011)

Responses of Pseudomonas aeruginosa to antimicrobials
por: Morita, Yuji, et al.
Publicado: (2014)

Antisense transcription in Pseudomonas aeruginosa
por: Eckweiler, Denitsa, et al.
Publicado: (2018)

Pyometra due to Pseudomonas aeruginosa
por: McLeod, Nathan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2bgla3vq23t9ne724ueeepcojh