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Interfering in the ALK1 Pathway Results in Macrophage-Driven Outward Remodeling of Murine Vein Grafts

AIMS: Vein grafts are frequently used to bypass coronary artery occlusions. Unfortunately, vein graft disease (VGD) causes impaired patency rates. ALK1 mediates signaling by TGF-β via TGFβR2 or BMP9/10 via BMPR2, which is an important pathway in fibrotic, inflammatory, and angiogenic processes in va...

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Detalles Bibliográficos
Autores principales:	de Jong, Alwin, Sier, Vincent Q., Peters, Hendrika A. B., Schilder, Natalia K. M., Jukema, J. Wouter, Goumans, Marie José T. H., Quax, Paul H. A., de Vries, Margreet R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850982/ https://www.ncbi.nlm.nih.gov/pubmed/35187106 http://dx.doi.org/10.3389/fcvm.2021.784980

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