Pharmacodynamics and Pharmacokinetics of HSK3486, a Novel 2,6-Disubstituted Phenol Derivative as a General Anesthetic

Background: The purpose of this study was to characterize the novel sedative/hypnotic agent HSK3486, a 2,6-disubstituted alkylphenol analogue. Methods: The mechanism of action of HSK3486 was studied in competitive binding assays and whole-cell patch clamp assays. HSK3486 was administered by bolus in...

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Detalles Bibliográficos
Autores principales: Liao, Juan, Li, Meiting, Huang, Chaoli, Yu, Yan, Chen, Yashu, Gan, Jiaqi, Xiao, Jie, Xiang, Guilin, Ding, Xizhi, Jiang, Rong, Li, Peng, Yang, Mengchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851058/
https://www.ncbi.nlm.nih.gov/pubmed/35185584
http://dx.doi.org/10.3389/fphar.2022.830791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851058/
https://www.ncbi.nlm.nih.gov/pubmed/35185584
http://dx.doi.org/10.3389/fphar.2022.830791

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