Hsp90 Inhibitors Prevent HSV-1 Replication by Directly Targeting UL42-Hsp90 Complex

Herpes simplex virus type I (HSV-1) is a member of the Alphaherpesvirinae family, which could initiate labial herpes caused by the reactivation of HSV-1 primary infection, and secondary infection even causes herpes encephalitis. The study presented here demonstrates that Hsp90 inhibitors (AT-533 and...

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Detalles Bibliográficos
Autores principales: Qin, Shurong, Hu, Xiao, Lin, Shimin, Xiao, Ji, Wang, Zhaoyang, Jia, Jiaoyan, Song, Xiaowei, Liu, Kaisheng, Ren, Zhe, Wang, Yifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851068/
https://www.ncbi.nlm.nih.gov/pubmed/35185822
http://dx.doi.org/10.3389/fmicb.2021.797279

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