Oncolytic Zika virus promotes intratumoral T cell infiltration and improves immunotherapy efficacy in glioblastoma

Glioblastoma (GBM) is the deadliest primary brain tumor and is generally resistant to immunotherapy because of severe dysfunction of T cells. Novel treatment options are critically needed to overcome the immunotherapy resistance of GBM. Here we demonstrate that Zika virus (ZIKV) treatment improves t...

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Detalles Bibliográficos
Autores principales: Chen, Lishu, Zhou, Chao, Chen, Qi, Shang, Jingzhe, Liu, Zhaodan, Guo, Yan, Li, Chunfeng, Wang, HongJiang, Ye, Qing, Li, XiaoFeng, Zu, Shulong, Li, Fangye, Xia, Qing, Zhou, Tao, Li, Ailing, Wang, Chenhui, Chen, Yun, Wu, Aiping, Qin, Chengfeng, Man, Jianghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851082/
https://www.ncbi.nlm.nih.gov/pubmed/35229030
http://dx.doi.org/10.1016/j.omto.2022.01.011

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