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Characterization of AAV-mediated dorsal root ganglionopathy

Recent studies in non-human primates administered recombinant adeno-associated viruses (rAAVs) have shown lesions in the dorsal root ganglia (DRG) of unknown pathogenesis. In this study, rAAV9s manufactured using different purification methods alongside a non-expressing Null AAV9 vector was administ...

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Detalles Bibliográficos
Autores principales:	Buss, Nicholas, Lanigan, Lisa, Zeller, Jillynne, Cissell, Derek, Metea, Monica, Adams, Eric, Higgins, Mikayla, Kim, Kwi Hye, Budzynski, Ewa, Yang, Lin, Liu, Ye, Butt, Mark, Danos, Olivier, Fiscella, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851102/ https://www.ncbi.nlm.nih.gov/pubmed/35229008 http://dx.doi.org/10.1016/j.omtm.2022.01.013

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