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IgA Vasculitis in an Oldest-old Patient Successfully Treated with Glucocorticoid
A 94-year-old man was diagnosed with immunoglobulin A vasculitis (IgAV), and losartan was initiated. His renal function rapidly deteriorated over a month; therefore, methylprednisolone was administered intravenously for three days followed by oral prednisolone. Renal function improvement and both pr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851165/ https://www.ncbi.nlm.nih.gov/pubmed/34176841 http://dx.doi.org/10.2169/internalmedicine.7576-21 |
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author | Sato, Hirotaka Takase, Kentaro Matsui, Kosuke Ishitobi, Tomoko Onuma, Hideyuki Kin, Seikon Ito, Takafumi |
author_facet | Sato, Hirotaka Takase, Kentaro Matsui, Kosuke Ishitobi, Tomoko Onuma, Hideyuki Kin, Seikon Ito, Takafumi |
author_sort | Sato, Hirotaka |
collection | PubMed |
description | A 94-year-old man was diagnosed with immunoglobulin A vasculitis (IgAV), and losartan was initiated. His renal function rapidly deteriorated over a month; therefore, methylprednisolone was administered intravenously for three days followed by oral prednisolone. Renal function improvement and both proteinuria and hematuria remission were observed within six months. Prednisolone tapering was completed at eight months. In this case, we monitored the patient carefully and started glucocorticoids as soon as the patient's renal function deteriorated. We were thus able to treat the patient with a relatively small dose of glucocorticoids in a short treatment period without any adverse events due to glucocorticoids. |
format | Online Article Text |
id | pubmed-8851165 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-88511652022-03-09 IgA Vasculitis in an Oldest-old Patient Successfully Treated with Glucocorticoid Sato, Hirotaka Takase, Kentaro Matsui, Kosuke Ishitobi, Tomoko Onuma, Hideyuki Kin, Seikon Ito, Takafumi Intern Med Case Report A 94-year-old man was diagnosed with immunoglobulin A vasculitis (IgAV), and losartan was initiated. His renal function rapidly deteriorated over a month; therefore, methylprednisolone was administered intravenously for three days followed by oral prednisolone. Renal function improvement and both proteinuria and hematuria remission were observed within six months. Prednisolone tapering was completed at eight months. In this case, we monitored the patient carefully and started glucocorticoids as soon as the patient's renal function deteriorated. We were thus able to treat the patient with a relatively small dose of glucocorticoids in a short treatment period without any adverse events due to glucocorticoids. The Japanese Society of Internal Medicine 2021-06-26 2022-01-15 /pmc/articles/PMC8851165/ /pubmed/34176841 http://dx.doi.org/10.2169/internalmedicine.7576-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Sato, Hirotaka Takase, Kentaro Matsui, Kosuke Ishitobi, Tomoko Onuma, Hideyuki Kin, Seikon Ito, Takafumi IgA Vasculitis in an Oldest-old Patient Successfully Treated with Glucocorticoid |
title | IgA Vasculitis in an Oldest-old Patient Successfully Treated with Glucocorticoid |
title_full | IgA Vasculitis in an Oldest-old Patient Successfully Treated with Glucocorticoid |
title_fullStr | IgA Vasculitis in an Oldest-old Patient Successfully Treated with Glucocorticoid |
title_full_unstemmed | IgA Vasculitis in an Oldest-old Patient Successfully Treated with Glucocorticoid |
title_short | IgA Vasculitis in an Oldest-old Patient Successfully Treated with Glucocorticoid |
title_sort | iga vasculitis in an oldest-old patient successfully treated with glucocorticoid |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851165/ https://www.ncbi.nlm.nih.gov/pubmed/34176841 http://dx.doi.org/10.2169/internalmedicine.7576-21 |
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