Carney Complex Complicated with Primary Pigmented Nodular Adrenocortical Disease without Cushing's Syndrome Recurrence for Five Years after Unilateral Adrenalectomy

We herein report a case of Carney complex (CNC) complicated with primary pigmented nodular adrenocortical disease (PPNAD) after unilateral adrenalectomy. A 44-year-old woman was admitted to our hospital for PPNAD surgery. She had previously undergone surgery for cardiac myxoma and had a PRKAR1A muta...

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Autores principales: Tsurutani, Yuya, Kiriyama, Kanako, Kondo, Mai, Hasebe, Masanori, Sata, Akira, Mizuno, Yuzo, Sugisawa, Chiho, Saito, Jun, Nishikawa, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851166/
https://www.ncbi.nlm.nih.gov/pubmed/35034934
http://dx.doi.org/10.2169/internalmedicine.7418-21
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author Tsurutani, Yuya
Kiriyama, Kanako
Kondo, Mai
Hasebe, Masanori
Sata, Akira
Mizuno, Yuzo
Sugisawa, Chiho
Saito, Jun
Nishikawa, Tetsuo
author_facet Tsurutani, Yuya
Kiriyama, Kanako
Kondo, Mai
Hasebe, Masanori
Sata, Akira
Mizuno, Yuzo
Sugisawa, Chiho
Saito, Jun
Nishikawa, Tetsuo
author_sort Tsurutani, Yuya
collection PubMed
description We herein report a case of Carney complex (CNC) complicated with primary pigmented nodular adrenocortical disease (PPNAD) after unilateral adrenalectomy. A 44-year-old woman was admitted to our hospital for PPNAD surgery. She had previously undergone surgery for cardiac myxoma and had a PRKAR1A mutation with no family history of CNC. She had Cushing's signs, but her metabolic abnormalities were mild. Adrenal insufficiency due to poor medication adherence was a concern, so she underwent unilateral adrenalectomy. Cushing's signs improved postoperatively and without recurrence for five years. Treatment plans for PPNAD should be determined based on the patient's condition, medication adherence, and wishes.
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spelling pubmed-88511662022-03-09 Carney Complex Complicated with Primary Pigmented Nodular Adrenocortical Disease without Cushing's Syndrome Recurrence for Five Years after Unilateral Adrenalectomy Tsurutani, Yuya Kiriyama, Kanako Kondo, Mai Hasebe, Masanori Sata, Akira Mizuno, Yuzo Sugisawa, Chiho Saito, Jun Nishikawa, Tetsuo Intern Med Case Report We herein report a case of Carney complex (CNC) complicated with primary pigmented nodular adrenocortical disease (PPNAD) after unilateral adrenalectomy. A 44-year-old woman was admitted to our hospital for PPNAD surgery. She had previously undergone surgery for cardiac myxoma and had a PRKAR1A mutation with no family history of CNC. She had Cushing's signs, but her metabolic abnormalities were mild. Adrenal insufficiency due to poor medication adherence was a concern, so she underwent unilateral adrenalectomy. Cushing's signs improved postoperatively and without recurrence for five years. Treatment plans for PPNAD should be determined based on the patient's condition, medication adherence, and wishes. The Japanese Society of Internal Medicine 2022-01-15 2022-01-15 /pmc/articles/PMC8851166/ /pubmed/35034934 http://dx.doi.org/10.2169/internalmedicine.7418-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Tsurutani, Yuya
Kiriyama, Kanako
Kondo, Mai
Hasebe, Masanori
Sata, Akira
Mizuno, Yuzo
Sugisawa, Chiho
Saito, Jun
Nishikawa, Tetsuo
Carney Complex Complicated with Primary Pigmented Nodular Adrenocortical Disease without Cushing's Syndrome Recurrence for Five Years after Unilateral Adrenalectomy
title Carney Complex Complicated with Primary Pigmented Nodular Adrenocortical Disease without Cushing's Syndrome Recurrence for Five Years after Unilateral Adrenalectomy
title_full Carney Complex Complicated with Primary Pigmented Nodular Adrenocortical Disease without Cushing's Syndrome Recurrence for Five Years after Unilateral Adrenalectomy
title_fullStr Carney Complex Complicated with Primary Pigmented Nodular Adrenocortical Disease without Cushing's Syndrome Recurrence for Five Years after Unilateral Adrenalectomy
title_full_unstemmed Carney Complex Complicated with Primary Pigmented Nodular Adrenocortical Disease without Cushing's Syndrome Recurrence for Five Years after Unilateral Adrenalectomy
title_short Carney Complex Complicated with Primary Pigmented Nodular Adrenocortical Disease without Cushing's Syndrome Recurrence for Five Years after Unilateral Adrenalectomy
title_sort carney complex complicated with primary pigmented nodular adrenocortical disease without cushing's syndrome recurrence for five years after unilateral adrenalectomy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851166/
https://www.ncbi.nlm.nih.gov/pubmed/35034934
http://dx.doi.org/10.2169/internalmedicine.7418-21
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