Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19

We herein report a case of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) triggered by COVID-19. An 87-year-old woman tested positive for COVID-19 on a polymerase chain reaction test, and computed tomography revealed ground-glass opacity (GGO) superimposed on a background pattern consi...

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Autores principales: Omote, Norihito, Kanemitsu, Yoshihiro, Inoue, Takahiro, Yonezawa, Toshiyuki, Ichihashi, Takuji, Shindo, Yuichiro, Sakamoto, Koji, Ando, Akira, Suzuki, Atsushi, Niimi, Akio, Ito, Satoru, Imaizumi, Kazuyoshi, Hashimoto, Naozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851168/
https://www.ncbi.nlm.nih.gov/pubmed/34744107
http://dx.doi.org/10.2169/internalmedicine.8163-21
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author Omote, Norihito
Kanemitsu, Yoshihiro
Inoue, Takahiro
Yonezawa, Toshiyuki
Ichihashi, Takuji
Shindo, Yuichiro
Sakamoto, Koji
Ando, Akira
Suzuki, Atsushi
Niimi, Akio
Ito, Satoru
Imaizumi, Kazuyoshi
Hashimoto, Naozumi
author_facet Omote, Norihito
Kanemitsu, Yoshihiro
Inoue, Takahiro
Yonezawa, Toshiyuki
Ichihashi, Takuji
Shindo, Yuichiro
Sakamoto, Koji
Ando, Akira
Suzuki, Atsushi
Niimi, Akio
Ito, Satoru
Imaizumi, Kazuyoshi
Hashimoto, Naozumi
author_sort Omote, Norihito
collection PubMed
description We herein report a case of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) triggered by COVID-19. An 87-year-old woman tested positive for COVID-19 on a polymerase chain reaction test, and computed tomography revealed ground-glass opacity (GGO) superimposed on a background pattern consistent with usual interstitial pneumonia. Considering these data, we diagnosed her with AE-IPF. She experienced worsening of dyspnea and expansion of the GGO. Therefore, we introduced high-dose steroids (methylprednisolone 250 mg/day for 3 days). After the treatment, the pulmonary infiltrates improved. She was discharged from our hospital without severe disability. High-dose steroids can be a viable treatment option for AE-IPF triggered by COVID-19.
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spelling pubmed-88511682022-02-28 Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19 Omote, Norihito Kanemitsu, Yoshihiro Inoue, Takahiro Yonezawa, Toshiyuki Ichihashi, Takuji Shindo, Yuichiro Sakamoto, Koji Ando, Akira Suzuki, Atsushi Niimi, Akio Ito, Satoru Imaizumi, Kazuyoshi Hashimoto, Naozumi Intern Med Case Report We herein report a case of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) triggered by COVID-19. An 87-year-old woman tested positive for COVID-19 on a polymerase chain reaction test, and computed tomography revealed ground-glass opacity (GGO) superimposed on a background pattern consistent with usual interstitial pneumonia. Considering these data, we diagnosed her with AE-IPF. She experienced worsening of dyspnea and expansion of the GGO. Therefore, we introduced high-dose steroids (methylprednisolone 250 mg/day for 3 days). After the treatment, the pulmonary infiltrates improved. She was discharged from our hospital without severe disability. High-dose steroids can be a viable treatment option for AE-IPF triggered by COVID-19. The Japanese Society of Internal Medicine 2021-11-06 2022-01-15 /pmc/articles/PMC8851168/ /pubmed/34744107 http://dx.doi.org/10.2169/internalmedicine.8163-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Omote, Norihito
Kanemitsu, Yoshihiro
Inoue, Takahiro
Yonezawa, Toshiyuki
Ichihashi, Takuji
Shindo, Yuichiro
Sakamoto, Koji
Ando, Akira
Suzuki, Atsushi
Niimi, Akio
Ito, Satoru
Imaizumi, Kazuyoshi
Hashimoto, Naozumi
Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19
title Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19
title_full Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19
title_fullStr Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19
title_full_unstemmed Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19
title_short Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19
title_sort successful treatment with high-dose steroids for acute exacerbation of idiopathic pulmonary fibrosis triggered by covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851168/
https://www.ncbi.nlm.nih.gov/pubmed/34744107
http://dx.doi.org/10.2169/internalmedicine.8163-21
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