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An UHPLC-MS/MS method for quantification of the CDK4/6 inhibitor abemaciclib in human serum
BACKGROUND: Abemaciclib is a new oral targeted treatment option for patients with advanced breast cancer. The emerging field of oral antitumor therapeutics presents challenges for both patients and healthcare teams; non-adherence and high inter-individual pharmacokinetic variability can influence re...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851261/ https://www.ncbi.nlm.nih.gov/pubmed/35199096 http://dx.doi.org/10.1016/j.jmsacl.2022.02.001 |