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REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2

Retinal pigment epithelium (RPE) dysfunction and atrophy occur in dry age-related macular degeneration (AMD), often leading to photoreceptor degeneration and vision loss. Accumulated oxidative stress during aging contributes to RPE dysfunction and degeneration. Here we show that the nuclear receptor...

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Detalles Bibliográficos
Autores principales:	Huang, Shuo, Liu, Chi-Hsiu, Wang, Zhongxiao, Fu, Zhongjie, Britton, William R., Blomfield, Alexandra K., Kamenecka, Theodore M., Dunaief, Joshua L., Solt, Laura A., Chen, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851379/ https://www.ncbi.nlm.nih.gov/pubmed/35176707 http://dx.doi.org/10.1016/j.redox.2022.102261

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