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Characteristics and Outcomes of Psoas Abscess: Experience From a Tertiary Care Center in North India

Background Psoas abscess (PA) is an uncommon disease involving infection of the psoas muscle with abscess formation. The evidence concerning clinical and diagnostic characteristics of PA and its outcomes is limited. The literature is heterogenous, with varying presentations and outcomes in different...

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Autores principales: Thakral, Ajay, Prasad, Divya, Katyal, Sachin, Kumar, Arvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851413/
https://www.ncbi.nlm.nih.gov/pubmed/35198272
http://dx.doi.org/10.7759/cureus.21358
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author Thakral, Ajay
Prasad, Divya
Katyal, Sachin
Kumar, Arvind
author_facet Thakral, Ajay
Prasad, Divya
Katyal, Sachin
Kumar, Arvind
author_sort Thakral, Ajay
collection PubMed
description Background Psoas abscess (PA) is an uncommon disease involving infection of the psoas muscle with abscess formation. The evidence concerning clinical and diagnostic characteristics of PA and its outcomes is limited. The literature is heterogenous, with varying presentations and outcomes in different regions worldwide. We present a retrospective analysis of the clinical, radiological, and laboratory characteristics of PA, its management, and outcomes from a tertiary care center in North India. Methodology We reviewed the clinical records of confirmed cases of PA treated in our institute from January 2016 to December 2020 with a minimum follow-up of one year. Further, we performed a descriptive analysis of demographic characteristics, clinical features, laboratory parameters, radiological investigations, the basis of diagnosis confirmation, causative microorganisms, definitive management, treatment outcomes, and complications. Results We reviewed 33 cases with a mean age of 29.9 ± 16.8 years. Overall, 48.4% of PAs were right-sided, and 24.2% were bilateral. Abdominal discomfort was the most common presenting symptom. Blood laboratory parameters were mostly within the near-normal range except for the elevated erythrocyte sedimentation rate, C-reactive protein, and neutrophil-to-lymphocyte ratio. Ultrasonography was the most commonly performed radiological investigation and was the basis of diagnosis confirmation. Mycobacterium tuberculosis was the most common causative microorganism. Most patients required percutaneous drainage, and around one-fourth required open drainage. All patients had symptomatic as well as radiological improvement and no major complications. Conclusions Tuberculosis is the most prevalent cause of PA in the North Indian population. Most patients respond well to the less invasive treatment with percutaneous therapeutic drainage and antitubercular drugs, with few patients requiring open drainage. However, tissue diagnosis may remain inconclusive in a few patients, and antitubercular treatment may need to be initiated based on the clinicoradiological evaluation. Nevertheless, the rate of complications is low, with nil mortality probably related to the mild-to-moderate disease course of tuberculosis.
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spelling pubmed-88514132022-02-22 Characteristics and Outcomes of Psoas Abscess: Experience From a Tertiary Care Center in North India Thakral, Ajay Prasad, Divya Katyal, Sachin Kumar, Arvind Cureus General Surgery Background Psoas abscess (PA) is an uncommon disease involving infection of the psoas muscle with abscess formation. The evidence concerning clinical and diagnostic characteristics of PA and its outcomes is limited. The literature is heterogenous, with varying presentations and outcomes in different regions worldwide. We present a retrospective analysis of the clinical, radiological, and laboratory characteristics of PA, its management, and outcomes from a tertiary care center in North India. Methodology We reviewed the clinical records of confirmed cases of PA treated in our institute from January 2016 to December 2020 with a minimum follow-up of one year. Further, we performed a descriptive analysis of demographic characteristics, clinical features, laboratory parameters, radiological investigations, the basis of diagnosis confirmation, causative microorganisms, definitive management, treatment outcomes, and complications. Results We reviewed 33 cases with a mean age of 29.9 ± 16.8 years. Overall, 48.4% of PAs were right-sided, and 24.2% were bilateral. Abdominal discomfort was the most common presenting symptom. Blood laboratory parameters were mostly within the near-normal range except for the elevated erythrocyte sedimentation rate, C-reactive protein, and neutrophil-to-lymphocyte ratio. Ultrasonography was the most commonly performed radiological investigation and was the basis of diagnosis confirmation. Mycobacterium tuberculosis was the most common causative microorganism. Most patients required percutaneous drainage, and around one-fourth required open drainage. All patients had symptomatic as well as radiological improvement and no major complications. Conclusions Tuberculosis is the most prevalent cause of PA in the North Indian population. Most patients respond well to the less invasive treatment with percutaneous therapeutic drainage and antitubercular drugs, with few patients requiring open drainage. However, tissue diagnosis may remain inconclusive in a few patients, and antitubercular treatment may need to be initiated based on the clinicoradiological evaluation. Nevertheless, the rate of complications is low, with nil mortality probably related to the mild-to-moderate disease course of tuberculosis. Cureus 2022-01-18 /pmc/articles/PMC8851413/ /pubmed/35198272 http://dx.doi.org/10.7759/cureus.21358 Text en Copyright © 2022, Thakral et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle General Surgery
Thakral, Ajay
Prasad, Divya
Katyal, Sachin
Kumar, Arvind
Characteristics and Outcomes of Psoas Abscess: Experience From a Tertiary Care Center in North India
title Characteristics and Outcomes of Psoas Abscess: Experience From a Tertiary Care Center in North India
title_full Characteristics and Outcomes of Psoas Abscess: Experience From a Tertiary Care Center in North India
title_fullStr Characteristics and Outcomes of Psoas Abscess: Experience From a Tertiary Care Center in North India
title_full_unstemmed Characteristics and Outcomes of Psoas Abscess: Experience From a Tertiary Care Center in North India
title_short Characteristics and Outcomes of Psoas Abscess: Experience From a Tertiary Care Center in North India
title_sort characteristics and outcomes of psoas abscess: experience from a tertiary care center in north india
topic General Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851413/
https://www.ncbi.nlm.nih.gov/pubmed/35198272
http://dx.doi.org/10.7759/cureus.21358
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