Cargando…
Deep Learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) With CT Images
A novel coronavirus (COVID-19) recently emerged as an acute respiratory syndrome, and has caused a pneumonia outbreak world-widely. As the COVID-19 continues to spread rapidly across the world, computed tomography (CT) has become essentially important for fast diagnoses. Thus, it is urgent to develo...
Formato: | Online Artículo Texto |
---|---|
Lenguaje: | English |
Publicado: |
IEEE
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851430/ https://www.ncbi.nlm.nih.gov/pubmed/33705321 http://dx.doi.org/10.1109/TCBB.2021.3065361 |
_version_ | 1784652818977652736 |
---|---|
collection | PubMed |
description | A novel coronavirus (COVID-19) recently emerged as an acute respiratory syndrome, and has caused a pneumonia outbreak world-widely. As the COVID-19 continues to spread rapidly across the world, computed tomography (CT) has become essentially important for fast diagnoses. Thus, it is urgent to develop an accurate computer-aided method to assist clinicians to identify COVID-19-infected patients by CT images. Here, we have collected chest CT scans of 88 patients diagnosed with COVID-19 from hospitals of two provinces in China, 100 patients infected with bacteria pneumonia, and 86 healthy persons for comparison and modeling. Based on the data, a deep learning-based CT diagnosis system was developed to identify patients with COVID-19. The experimental results showed that our model could accurately discriminate the COVID-19 patients from the bacteria pneumonia patients with an AUC of 0.95, recall (sensitivity) of 0.96, and precision of 0.79. When integrating three types of CT images, our model achieved a recall of 0.93 with precision of 0.86 for discriminating COVID-19 patients from others. Moreover, our model could extract main lesion features, especially the ground-glass opacity (GGO), which are visually helpful for assisted diagnoses by doctors. An online server is available for online diagnoses with CT images by our server (http://biomed.nscc-gz.cn/model.php). Source codes and datasets are available at our GitHub (https://github.com/SY575/COVID19-CT). |
format | Online Article Text |
id | pubmed-8851430 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | IEEE |
record_format | MEDLINE/PubMed |
spelling | pubmed-88514302022-05-13 Deep Learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) With CT Images IEEE/ACM Trans Comput Biol Bioinform Article A novel coronavirus (COVID-19) recently emerged as an acute respiratory syndrome, and has caused a pneumonia outbreak world-widely. As the COVID-19 continues to spread rapidly across the world, computed tomography (CT) has become essentially important for fast diagnoses. Thus, it is urgent to develop an accurate computer-aided method to assist clinicians to identify COVID-19-infected patients by CT images. Here, we have collected chest CT scans of 88 patients diagnosed with COVID-19 from hospitals of two provinces in China, 100 patients infected with bacteria pneumonia, and 86 healthy persons for comparison and modeling. Based on the data, a deep learning-based CT diagnosis system was developed to identify patients with COVID-19. The experimental results showed that our model could accurately discriminate the COVID-19 patients from the bacteria pneumonia patients with an AUC of 0.95, recall (sensitivity) of 0.96, and precision of 0.79. When integrating three types of CT images, our model achieved a recall of 0.93 with precision of 0.86 for discriminating COVID-19 patients from others. Moreover, our model could extract main lesion features, especially the ground-glass opacity (GGO), which are visually helpful for assisted diagnoses by doctors. An online server is available for online diagnoses with CT images by our server (http://biomed.nscc-gz.cn/model.php). Source codes and datasets are available at our GitHub (https://github.com/SY575/COVID19-CT). IEEE 2021-03-11 /pmc/articles/PMC8851430/ /pubmed/33705321 http://dx.doi.org/10.1109/TCBB.2021.3065361 Text en This article is free to access and download, along with rights for full text and data mining, re-use and analysis. |
spellingShingle | Article Deep Learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) With CT Images |
title | Deep Learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) With CT Images |
title_full | Deep Learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) With CT Images |
title_fullStr | Deep Learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) With CT Images |
title_full_unstemmed | Deep Learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) With CT Images |
title_short | Deep Learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) With CT Images |
title_sort | deep learning enables accurate diagnosis of novel coronavirus (covid-19) with ct images |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851430/ https://www.ncbi.nlm.nih.gov/pubmed/33705321 http://dx.doi.org/10.1109/TCBB.2021.3065361 |
work_keys_str_mv | AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages AT deeplearningenablesaccuratediagnosisofnovelcoronaviruscovid19withctimages |