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Simple and Economical Process for Producing Amantadine Hydrochloride

[Image: see text] A simple and economical process for producing amantadine hydrochloride (1) on a 250 g scale, an antiviral and anti-Parkinson drug, has been developed. Several methods for the preparation of 1 through intermediate N-(1-adamantyl)-acetamide (4) in four or three steps were reported. T...

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Detalles Bibliográficos
Autores principales:	Phan Thi, Phuong Dung, Dang, Tuan Anh, Vu, Binh Duong, Phan, Dinh Chau
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851435/ https://www.ncbi.nlm.nih.gov/pubmed/35187298 http://dx.doi.org/10.1021/acsomega.1c04652

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