TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation

Autophagy is a fundamental cellular process of protein degradation and recycling that regulates immune signaling pathways via multiple mechanisms. However, it remains unclear how autophagy epigenetically regulates the immune response. Here, we identified TRIM14 as an epigenetic regulator that reduce...

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Detalles Bibliográficos
Autores principales: Liu, Di, Zhao, Zhiyao, She, Yuanchu, Zhang, Lei, Chen, Xiangtian, Ma, Ling, Cui, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851536/
https://www.ncbi.nlm.nih.gov/pubmed/35145029
http://dx.doi.org/10.1073/pnas.2113454119

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