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Riboflavin Stabilizes Abasic, Oxidized G-Quadruplex Structures

[Image: see text] The G-quadruplex is a noncanonical fold of DNA commonly found at telomeres and within gene promoter regions of the genome. These guanine-rich sequences are highly susceptible to damages such as base oxidation and depurination, leading to abasic sites. In the present work, we addres...

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Detalles Bibliográficos
Autores principales:	Galindo-Murillo, Rodrigo, Winkler, Lauren, Ma, Jingwei, Hanelli, Fatjon, Fleming, Aaron M., Burrows, Cynthia J., Cheatham, Thomas E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851688/ https://www.ncbi.nlm.nih.gov/pubmed/35104101 http://dx.doi.org/10.1021/acs.biochem.1c00598

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