Antibody attributes that predict the neutralization and effector function of polyclonal responses to SARS-CoV-2

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BACKGROUND: While antibodies can provide significant protection from SARS-CoV-2 infection and disease sequelae, the specific attributes of the humoral response that contribute to immunity are incompletely defined. METHODS: We employ machine learning to relate characteristics of the polyclonal antibo...

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Detalles Bibliográficos
Autores principales: Natarajan, Harini, Xu, Shiwei, Crowley, Andrew R., Butler, Savannah E., Weiner, Joshua A., Bloch, Evan M., Littlefield, Kirsten, Benner, Sarah E., Shrestha, Ruchee, Ajayi, Olivia, Wieland-Alter, Wendy, Sullivan, David, Shoham, Shmuel, Quinn, Thomas C., Casadevall, Arturo, Pekosz, Andrew, Redd, Andrew D., Tobian, Aaron A. R., Connor, Ruth I., Wright, Peter F., Ackerman, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851712/
https://www.ncbi.nlm.nih.gov/pubmed/35172720
http://dx.doi.org/10.1186/s12865-022-00480-w
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