Loss of REST in breast cancer promotes tumor progression through estrogen sensitization, MMP24 and CEMIP overexpression

BACKGROUND: Breast cancer is the most common malignancy in women, and is both pathologically and genetically heterogeneous, making early detection and treatment difficult. A subset of breast cancers express normal levels of REST (repressor element 1 silencing transcription factor) mRNA but lack func...

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Detalles Bibliográficos
Autores principales: Cloud, Ashley S., Vargheese, Aditya M., Gunewardena, Sumedha, Shimak, Raeann M., Ganeshkumar, Sornakala, Kumaraswamy, Easwari, Jensen, Roy A., Chennathukuzhi, Vargheese M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851790/
https://www.ncbi.nlm.nih.gov/pubmed/35177031
http://dx.doi.org/10.1186/s12885-022-09280-2

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