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Plasmodium Circumsporozoite Protein Enhances the Efficacy of Gefitinib in Lung Adenocarcinoma Cells by Inhibiting Autophagy via Proteasomal Degradation of LC3B

Background: Almost all lung adenocarcinoma (LUAD) patients with EGFR mutant will develop resistance to EGFR-TKIs, which limit the long-term clinical application of these agents. Accumulating evidence shows one of the main reasons for resistance to EGFR-TKIs is induction of autophagy in tumor cells....

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Detalles Bibliográficos
Autores principales:	Lu, Xiao, Zhang, Jiao, Li, Yan-Qi, Liu, Quan-Xing, Zhou, Dong, Deng, Xu-Feng, Qiu, Yuan, Chen, Qian, Li, Man-Yuan, Liu, Xiao-Qing, Dai, Ji-Gang, Zheng, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851824/ https://www.ncbi.nlm.nih.gov/pubmed/35186935 http://dx.doi.org/10.3389/fcell.2022.830046

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