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Heterocellular N-cadherin junctions enable nontransformed cells to inhibit the growth of adjacent transformed cells

BACKGROUND: The Src tyrosine kinase phosphorylates effector proteins to induce expression of the podoplanin (PDPN) receptor in order to promote tumor progression. However, nontransformed cells can normalize the growth and morphology of neighboring transformed cells. Transformed cells must escape thi...

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Detalles Bibliográficos
Autores principales:	Sheehan, Stephanie A., Retzbach, Edward P., Shen, Yongquan, Krishnan, Harini, Goldberg, Gary S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851851/ https://www.ncbi.nlm.nih.gov/pubmed/35177067 http://dx.doi.org/10.1186/s12964-021-00817-9

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