Cargando…
Circ_FURIN knockdown assuages Testosterone-induced human ovarian granulosa-like tumor cell disorders by sponging miR-423-5p to reduce MTM1 expression in polycystic ovary syndrome
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder among reproductive-age women. The mechanism by which circular RNA (circRNA) drives PCOS development remains unclear. Thus, the study is designed to explore the role of a novel circRNA, circ_FURIN, in the PCOS cell model and...
Autores principales: | Xu, Xia, Guan, Rui, Gong, Ke, Xie, Huaibing, Shi, Lei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851856/ https://www.ncbi.nlm.nih.gov/pubmed/35177076 http://dx.doi.org/10.1186/s12958-022-00891-9 |
Ejemplares similares
-
Proprotein Convertase Furin Regulates Apoptosis and Proliferation of Granulosa Cells in the Rat Ovary
por: Yang, Xiaokui, et al.
Publicado: (2013) -
miR-423 sponged by lncRNA NORHA inhibits granulosa cell apoptosis
por: Li, Yuqi, et al.
Publicado: (2023) -
Knockdown of circ-FURIN suppresses the proliferation and induces apoptosis of granular cells in polycystic ovary syndrome via miR-195-5p/BCL2 axis
por: Chen, Yongqian, et al.
Publicado: (2021) -
Knockdown of circ_0113656 assuages oxidized low-density lipoprotein-induced vascular smooth muscle cell injury through the miR-188-3p/IGF2 pathway
por: Yang, Ming, et al.
Publicado: (2023) -
Circ_0043532 regulates miR-182/SGK3 axis to promote granulosa cell progression in polycystic ovary syndrome
por: Xu, Lishuang, et al.
Publicado: (2021)