Cargando…
The effect of prostacyclin infusion on markers of endothelial activation and damage in mechanically ventilated patients with SARS-CoV-2 infection
BACKGROUND: In a pilot study, we found a significant reduction in mean daily sequential organ failure assessment score in mechanically ventilated patients with COVID-19 who received prostacyclin, compared to placebo. We here investigate the effect on biomarkers of endothelial activation and damage....
Autores principales: | Vigstedt, Martin, Søe-Jensen, Peter, Bestle, Morten H., Clausen, Niels E., Kristiansen, Klaus T., Lange, Theis, Stensballe, Jakob, Perner, Anders, Johansson, Pär I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851884/ https://www.ncbi.nlm.nih.gov/pubmed/35183892 http://dx.doi.org/10.1016/j.jcrc.2022.154010 |
Ejemplares similares
-
Prostacyclin in Intubated Patients with COVID-19 and Severe Endotheliopathy: A Multicenter, Randomized Clinical Trial
por: Johansson, Pär I., et al.
Publicado: (2021) -
The effect of prostacyclin (Iloprost) infusion at a dose of 1 ng/kg/min for 72 hours compared to placebo in mechanically ventilated patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial
por: Johansson, Pär Ingemar, et al.
Publicado: (2020) -
Efficacy and safety of iloprost in patients with septic shock‐induced endotheliopathy—Protocol for the multicenter randomized, placebo‐controlled, blinded, investigator‐initiated trial
por: Bestle, Morten H., et al.
Publicado: (2020) -
Endotheliopathy is associated with slower liberation from mechanical ventilation: a cohort study
por: Schønemann-Lund, Martin, et al.
Publicado: (2022) -
Forced fluid removal versus usual care in intensive care patients with high-risk acute kidney injury and severe fluid overload (FFAKI): study protocol for a randomised controlled pilot trial
por: Berthelsen, Rasmus E., et al.
Publicado: (2017)