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Crinecerfont Lowers Elevated Hormone Markers in Adults With 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia

CONTEXT: Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21OHD) is characterized by impaired cortisol synthesis and excess androgen production. Corticotropin-releasing factor type 1 receptor (CRF1R) antagonism may decrease adrenal androgen production. OBJECTIVE: This work ai...

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Detalles Bibliográficos
Autores principales:	Auchus, Richard J, Sarafoglou, Kyriakie, Fechner, Patricia Y, Vogiatzi, Maria G, Imel, Erik A, Davis, Shanlee M, Giri, Nagdeep, Sturgeon, Julia, Roberts, Eiry, Chan, Jean L, Farber, Robert H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Clinical Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851935/ https://www.ncbi.nlm.nih.gov/pubmed/34653252 http://dx.doi.org/10.1210/clinem/dgab749

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