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Multi-omics analyses of the Ulcerative Colitis gut microbiome link Bacteroides vulgatus proteases with disease severity

Ulcerative colitis (UC) is driven by disruptions in host-microbiota homeostasis, however current treatments exclusively target host inflammatory pathways. To understand how host-microbiota interactions become disrupted in UC, we collected and analyzed six fecal or serum based –omic datasets (metapro...

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Detalles Bibliográficos
Autores principales: Mills, Robert H., Dulai, Parambir S., Vázquez-Baeza, Yoshiki, Sauceda, Consuelo, Daniel, Noëmie, Gerner, Romana R., Batachari, Lakshmi E., Ochoa, Mario Malfavon, Zhu, Qiyun, Weldon, Kelly, Humphrey, Greg, Carrillo-Terrazas, Marvic, Goldasich, Lindsay DeRight, Bryant, MacKenzie, Raffatellu, Manuela, Quinn, Robert A., Gewirtz, Andrew T., Chassaing, Benoit, Chu, Hiutung, Sandborn, William J., Dorrestein, Pieter C., Knight, Rob, Gonzalez, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852248/
https://www.ncbi.nlm.nih.gov/pubmed/35087228
http://dx.doi.org/10.1038/s41564-021-01050-3