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Case Report: Cerebral Nocardiosis Caused by Nocardia cyriacigeorgica Detected by Metagenomics in an Apparently Immunocompetent Patient

We report a case of meningoencephalitis due to Nocardia cyriacigeorgica diagnosed with metagenomics, while all the standard methods were negative. This diagnosis made adaptation of antimicrobial treatment possible and led to the discovery of a rare, acquired immunodeficiency syndrome.

Detalles Bibliográficos
Autores principales: Courbin, Virginie, Riller, Quentin, Amegnizin, Jean-Louis, Gricourt, Guillaume, Demontant, Vanessa, Fihman, Vincent, Angebault, Cecile, Mahevas, Matthieu, Gaube, Géraldine, Coutte, Laëtitia, Pawlotsky, Jean-Michel, Lepeule, Raphaël, Rodriguez, Christophe, Woerther, Paul-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852340/
https://www.ncbi.nlm.nih.gov/pubmed/35185867
http://dx.doi.org/10.3389/fimmu.2022.719124
Descripción
Sumario:We report a case of meningoencephalitis due to Nocardia cyriacigeorgica diagnosed with metagenomics, while all the standard methods were negative. This diagnosis made adaptation of antimicrobial treatment possible and led to the discovery of a rare, acquired immunodeficiency syndrome.