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Case Report: Cerebral Nocardiosis Caused by Nocardia cyriacigeorgica Detected by Metagenomics in an Apparently Immunocompetent Patient

We report a case of meningoencephalitis due to Nocardia cyriacigeorgica diagnosed with metagenomics, while all the standard methods were negative. This diagnosis made adaptation of antimicrobial treatment possible and led to the discovery of a rare, acquired immunodeficiency syndrome.

Detalles Bibliográficos
Autores principales: Courbin, Virginie, Riller, Quentin, Amegnizin, Jean-Louis, Gricourt, Guillaume, Demontant, Vanessa, Fihman, Vincent, Angebault, Cecile, Mahevas, Matthieu, Gaube, Géraldine, Coutte, Laëtitia, Pawlotsky, Jean-Michel, Lepeule, Raphaël, Rodriguez, Christophe, Woerther, Paul-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852340/
https://www.ncbi.nlm.nih.gov/pubmed/35185867
http://dx.doi.org/10.3389/fimmu.2022.719124
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author Courbin, Virginie
Riller, Quentin
Amegnizin, Jean-Louis
Gricourt, Guillaume
Demontant, Vanessa
Fihman, Vincent
Angebault, Cecile
Mahevas, Matthieu
Gaube, Géraldine
Coutte, Laëtitia
Pawlotsky, Jean-Michel
Lepeule, Raphaël
Rodriguez, Christophe
Woerther, Paul-Louis
author_facet Courbin, Virginie
Riller, Quentin
Amegnizin, Jean-Louis
Gricourt, Guillaume
Demontant, Vanessa
Fihman, Vincent
Angebault, Cecile
Mahevas, Matthieu
Gaube, Géraldine
Coutte, Laëtitia
Pawlotsky, Jean-Michel
Lepeule, Raphaël
Rodriguez, Christophe
Woerther, Paul-Louis
author_sort Courbin, Virginie
collection PubMed
description We report a case of meningoencephalitis due to Nocardia cyriacigeorgica diagnosed with metagenomics, while all the standard methods were negative. This diagnosis made adaptation of antimicrobial treatment possible and led to the discovery of a rare, acquired immunodeficiency syndrome.
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spelling pubmed-88523402022-02-18 Case Report: Cerebral Nocardiosis Caused by Nocardia cyriacigeorgica Detected by Metagenomics in an Apparently Immunocompetent Patient Courbin, Virginie Riller, Quentin Amegnizin, Jean-Louis Gricourt, Guillaume Demontant, Vanessa Fihman, Vincent Angebault, Cecile Mahevas, Matthieu Gaube, Géraldine Coutte, Laëtitia Pawlotsky, Jean-Michel Lepeule, Raphaël Rodriguez, Christophe Woerther, Paul-Louis Front Immunol Cellular and Infection Microbiology We report a case of meningoencephalitis due to Nocardia cyriacigeorgica diagnosed with metagenomics, while all the standard methods were negative. This diagnosis made adaptation of antimicrobial treatment possible and led to the discovery of a rare, acquired immunodeficiency syndrome. Frontiers Media S.A. 2022-02-03 /pmc/articles/PMC8852340/ /pubmed/35185867 http://dx.doi.org/10.3389/fimmu.2022.719124 Text en Copyright © 2022 Courbin, Riller, Amegnizin, Gricourt, Demontant, Fihman, Angebault, Mahevas, Gaube, Coutte, Pawlotsky, Lepeule, Rodriguez and Woerther https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Courbin, Virginie
Riller, Quentin
Amegnizin, Jean-Louis
Gricourt, Guillaume
Demontant, Vanessa
Fihman, Vincent
Angebault, Cecile
Mahevas, Matthieu
Gaube, Géraldine
Coutte, Laëtitia
Pawlotsky, Jean-Michel
Lepeule, Raphaël
Rodriguez, Christophe
Woerther, Paul-Louis
Case Report: Cerebral Nocardiosis Caused by Nocardia cyriacigeorgica Detected by Metagenomics in an Apparently Immunocompetent Patient
title Case Report: Cerebral Nocardiosis Caused by Nocardia cyriacigeorgica Detected by Metagenomics in an Apparently Immunocompetent Patient
title_full Case Report: Cerebral Nocardiosis Caused by Nocardia cyriacigeorgica Detected by Metagenomics in an Apparently Immunocompetent Patient
title_fullStr Case Report: Cerebral Nocardiosis Caused by Nocardia cyriacigeorgica Detected by Metagenomics in an Apparently Immunocompetent Patient
title_full_unstemmed Case Report: Cerebral Nocardiosis Caused by Nocardia cyriacigeorgica Detected by Metagenomics in an Apparently Immunocompetent Patient
title_short Case Report: Cerebral Nocardiosis Caused by Nocardia cyriacigeorgica Detected by Metagenomics in an Apparently Immunocompetent Patient
title_sort case report: cerebral nocardiosis caused by nocardia cyriacigeorgica detected by metagenomics in an apparently immunocompetent patient
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852340/
https://www.ncbi.nlm.nih.gov/pubmed/35185867
http://dx.doi.org/10.3389/fimmu.2022.719124
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