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CR-I-TASSER: Assemble Protein Structures from Cryo-EM Density Maps using Deep Convolutional Neural Networks
Cryo-electron microscopy (cryo-EM) has become a leading approach for protein structure determination, but it remains challenging to accurately model atomic structures with cryo-EM density maps. We propose a hybrid method, CR-I-TASSER, which integrates deep neural-network learning with I-TASSER assem...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852347/ https://www.ncbi.nlm.nih.gov/pubmed/35132244 http://dx.doi.org/10.1038/s41592-021-01389-9 |