A Computer-Aided Approach for the Discovery of D-Peptides as Inhibitors of SARS-CoV-2 Main Protease

The SARS-CoV-2 main protease, also known as 3-chymotrypsin-like protease (3CL(pro)), is a cysteine protease responsible for the cleavage of viral polyproteins pp1a and pp1ab, at least, at eleven conserved sites, which leads to the formation of mature nonstructural proteins essential for the replicat...

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Detalles Bibliográficos
Autores principales: Hernández González, Jorge E., Eberle, Raphael J., Willbold, Dieter, Coronado, Mônika A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852625/
https://www.ncbi.nlm.nih.gov/pubmed/35187076
http://dx.doi.org/10.3389/fmolb.2021.816166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852625/
https://www.ncbi.nlm.nih.gov/pubmed/35187076
http://dx.doi.org/10.3389/fmolb.2021.816166

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