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Distinct Serotypes of Streptococcal M Proteins Mediate Fibrinogen-Dependent Platelet Activation and Proinflammatory Effects

Sepsis is a life-threatening complication of infection that is characterized by a dysregulated inflammatory state and disturbed hemostasis. Platelets are the main regulators of hemostasis, and they also respond to inflammation. The human pathogen Streptococcus pyogenes can cause local infection that...

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Detalles Bibliográficos
Autores principales: Palm, Frida, Chowdhury, Sounak, Wettemark, Sara, Malmström, Johan, Happonen, Lotta, Shannon, Oonagh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852700/
https://www.ncbi.nlm.nih.gov/pubmed/34898252
http://dx.doi.org/10.1128/iai.00462-21