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Distinct Serotypes of Streptococcal M Proteins Mediate Fibrinogen-Dependent Platelet Activation and Proinflammatory Effects
Sepsis is a life-threatening complication of infection that is characterized by a dysregulated inflammatory state and disturbed hemostasis. Platelets are the main regulators of hemostasis, and they also respond to inflammation. The human pathogen Streptococcus pyogenes can cause local infection that...
Autores principales: | Palm, Frida, Chowdhury, Sounak, Wettemark, Sara, Malmström, Johan, Happonen, Lotta, Shannon, Oonagh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852700/ https://www.ncbi.nlm.nih.gov/pubmed/34898252 http://dx.doi.org/10.1128/iai.00462-21 |
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