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Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease

BACKGROUND & AIMS: There is substantial inter-individual variability in the risk of non-alcoholic fatty liver disease (NAFLD). Part of which is explained by insulin resistance (IR) (‘MetComp’) and part by common modifiers of genetic risk (‘GenComp’). We examined how IR on the one hand and geneti...

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Detalles Bibliográficos
Autores principales:	Luukkonen, Panu K., Qadri, Sami, Ahlholm, Noora, Porthan, Kimmo, Männistö, Ville, Sammalkorpi, Henna, Penttilä, Anne K., Hakkarainen, Antti, Lehtimäki, Tiina E., Gaggini, Melania, Gastaldelli, Amalia, Ala-Korpela, Mika, Orho-Melander, Marju, Arola, Johanna, Juuti, Anne, Pihlajamäki, Jussi, Hodson, Leanne, Yki-Järvinen, Hannele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852745/ https://www.ncbi.nlm.nih.gov/pubmed/34710482 http://dx.doi.org/10.1016/j.jhep.2021.10.013

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