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Unraveling the differential impact of PAHs and dioxin-like compounds on AKR1C3 reveals the EGFR extracellular domain as a critical determinant of the AHR response

Polycyclic aromatic hydrocarbons (PAHs), dioxin-like compounds (DLCs) and structurally-related environmental pollutants may contribute to the pathogenesis of various diseases and disorders, primarily by activating the aryl hydrocarbon receptor (AHR) and modulating downstream cellular responses. Acco...

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Detalles Bibliográficos
Autores principales:	Vogeley, Christian, Sondermann, Natalie C., Woeste, Selina, Momin, Afaque A., Gilardino, Viola, Hartung, Frederick, Heinen, Markus, Maaß, Sophia K., Mescher, Melina, Pollet, Marius, Rolfes, Katharina M., Vogel, Christoph F.A., Rossi, Andrea, Lang, Dieter, Arold, Stefan T., Nakamura, Motoki, Haarmann-Stemmann, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852774/ https://www.ncbi.nlm.nih.gov/pubmed/34991250 http://dx.doi.org/10.1016/j.envint.2021.106989

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