T cell responses to SARS-CoV-2 in humans and animals

SARS-CoV-2, the causative agent of COVID-19, first emerged in 2019. Antibody responses against SARS-CoV-2 have been given a lot of attention. However, the armamentarium of humoral and T cells may have differing roles in different viral infections. Though the exact role of T cells in COVID-19 remains...

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Detalles Bibliográficos
Autores principales: Mattoo, Sameer-ul-Salam, Myoung, Jinjong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Microbiological Society of Korea 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852923/
https://www.ncbi.nlm.nih.gov/pubmed/35157219
http://dx.doi.org/10.1007/s12275-022-1624-z
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author Mattoo, Sameer-ul-Salam
Myoung, Jinjong
author_facet Mattoo, Sameer-ul-Salam
Myoung, Jinjong
author_sort Mattoo, Sameer-ul-Salam
collection PubMed
description SARS-CoV-2, the causative agent of COVID-19, first emerged in 2019. Antibody responses against SARS-CoV-2 have been given a lot of attention. However, the armamentarium of humoral and T cells may have differing roles in different viral infections. Though the exact role of T cells in COVID-19 remains to be elucidated, prior experience with human coronavirus has revealed an essential role of T cells in the outcomes of viral infections. Moreover, an increasing body of evidence suggests that T cells might be effective against SARS-CoV-2. This review summarizes the role of T cells in mouse CoV, human pathogenic respiratory CoV in general and SARS-CoV-2 in specific.
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spelling pubmed-88529232022-02-18 T cell responses to SARS-CoV-2 in humans and animals Mattoo, Sameer-ul-Salam Myoung, Jinjong J Microbiol Review SARS-CoV-2, the causative agent of COVID-19, first emerged in 2019. Antibody responses against SARS-CoV-2 have been given a lot of attention. However, the armamentarium of humoral and T cells may have differing roles in different viral infections. Though the exact role of T cells in COVID-19 remains to be elucidated, prior experience with human coronavirus has revealed an essential role of T cells in the outcomes of viral infections. Moreover, an increasing body of evidence suggests that T cells might be effective against SARS-CoV-2. This review summarizes the role of T cells in mouse CoV, human pathogenic respiratory CoV in general and SARS-CoV-2 in specific. The Microbiological Society of Korea 2022-02-14 2022 /pmc/articles/PMC8852923/ /pubmed/35157219 http://dx.doi.org/10.1007/s12275-022-1624-z Text en © The Microbiological Society of Korea 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review
Mattoo, Sameer-ul-Salam
Myoung, Jinjong
T cell responses to SARS-CoV-2 in humans and animals
title T cell responses to SARS-CoV-2 in humans and animals
title_full T cell responses to SARS-CoV-2 in humans and animals
title_fullStr T cell responses to SARS-CoV-2 in humans and animals
title_full_unstemmed T cell responses to SARS-CoV-2 in humans and animals
title_short T cell responses to SARS-CoV-2 in humans and animals
title_sort t cell responses to sars-cov-2 in humans and animals
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852923/
https://www.ncbi.nlm.nih.gov/pubmed/35157219
http://dx.doi.org/10.1007/s12275-022-1624-z
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