Cargando…
Identification of nafamostat mesylate as a selective stimulator of NK cell IFN-γ production via metabolism-related compound library screening
Natural killer (NK) cells play important roles in controlling virus-infected and malignant cells. The identification of new molecules that can activate NK cells may effectively improve the antiviral and antitumour activities of these cells. In this study, by using a commercially available metabolism...
Autores principales: | Yang, Qinglan, Zhang, Shuju, Wu, Shuting, Yao, Baige, Wang, Lili, Li, Yana, Peng, Hongyan, Huang, Minghui, Bi, Qinghua, Xiong, Peiwen, Li, Liping, Deng, Yafei, Deng, Youcai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852993/ https://www.ncbi.nlm.nih.gov/pubmed/35167033 http://dx.doi.org/10.1007/s12026-022-09266-z |
Ejemplares similares
-
Screening for Active Compounds Targeting Human Natural Killer Cell Activation Identifying Daphnetin as an Enhancer for IFN-γ Production and Direct Cytotoxicity
por: Yao, Baige, et al.
Publicado: (2021) -
Conditional knockout of Tsc1 in RORγt-expressing cells induces brain damage and early death in mice
por: Deng, Yafei, et al.
Publicado: (2021) -
Docosahexaenoic acid supplementation represses the early immune response against murine cytomegalovirus but enhances NK cell effector function
por: Wu, Shuting, et al.
Publicado: (2022) -
Sex differences exist in adult heart group 2 innate lymphoid cells
por: Peng, Hongyan, et al.
Publicado: (2022) -
Nafamostat mesylate attenuates the pathophysiologic sequelae of neurovascular ischemia
por: Ghali, George Zaki, et al.
Publicado: (2020)