(1)H, (13)C and (15)N resonance assignments of stress granule key component G3BP1 RRM domain

G3BP1 exists as a helicase and one of the core components in stress granules, which are associated with a variety of neurodegenerative diseases. Its RNA recognition motif (RRM) domain performs the paramount function of binding mRNA. Here we report the resonance assignment of human G3BP1 RRM domain t...

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Detalles Bibliográficos
Autores principales: Zhang, Hanyu, Tu, Xiaoming, Zhang, Jiahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853222/
https://www.ncbi.nlm.nih.gov/pubmed/35150414
http://dx.doi.org/10.1007/s12104-022-10067-6
Descripción
Sumario:G3BP1 exists as a helicase and one of the core components in stress granules, which are associated with a variety of neurodegenerative diseases. Its RNA recognition motif (RRM) domain performs the paramount function of binding mRNA. Here we report the resonance assignment of human G3BP1 RRM domain to understand its structure–function relationship.

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