Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance

Multidrug-resistant Plasmodium falciparum parasites have emerged in Cambodia and neighboring countries in Southeast Asia, compromising the efficacy of first-line antimalarial combinations. Dihydroartemisinin + piperaquine (PPQ) treatment failure rates have risen to as high as 50% in some areas in th...

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Detalles Bibliográficos
Autores principales: Small-Saunders, Jennifer L., Hagenah, Laura M., Wicht, Kathryn J., Dhingra, Satish K., Deni, Ioanna, Kim, Jonathan, Vendome, Jeremie, Gil-Iturbe, Eva, Roepe, Paul D., Mehta, Monica, Mancia, Filippo, Quick, Matthias, Eppstein, Margaret J., Fidock, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853508/
https://www.ncbi.nlm.nih.gov/pubmed/35130315
http://dx.doi.org/10.1371/journal.ppat.1010278

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