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Exotoxin S secreted by internalized Pseudomonas aeruginosa delays lytic host cell death

The Pseudomonas aeruginosa toxin ExoS, secreted by the type III secretion system (T3SS), supports intracellular persistence via its ADP-ribosyltransferase (ADPr) activity. For epithelial cells, this involves inhibiting vacuole acidification, promoting vacuolar escape, countering autophagy, and niche...

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Detalles Bibliográficos
Autores principales:	Kroken, Abby R., Gajenthra Kumar, Naren, Yahr, Timothy L., Smith, Benjamin E., Nieto, Vincent, Horneman, Hart, Evans, David J., Fleiszig, Suzanne M. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853526/ https://www.ncbi.nlm.nih.gov/pubmed/35130333 http://dx.doi.org/10.1371/journal.ppat.1010306

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