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INTEGRATE: Model-based multi-omics data integration to characterize multi-level metabolic regulation
Metabolism is directly and indirectly fine-tuned by a complex web of interacting regulatory mechanisms that fall into two major classes. On the one hand, the expression level of the catalyzing enzyme sets the maximal theoretical flux level (i.e., the net rate of the reaction) for each enzyme-control...
Autores principales: | Di Filippo, Marzia, Pescini, Dario, Galuzzi, Bruno Giovanni, Bonanomi, Marcella, Gaglio, Daniela, Mangano, Eleonora, Consolandi, Clarissa, Alberghina, Lilia, Vanoni, Marco, Damiani, Chiara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853556/ https://www.ncbi.nlm.nih.gov/pubmed/35130273 http://dx.doi.org/10.1371/journal.pcbi.1009337 |
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