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Insights into POT1 structural dynamics revealed by cryo-EM

Telomeres are protein-DNA complexes that protect the ends of linear eukaryotic chromosomes. Mammalian telomeric DNA consists of 5′-(TTAGGG)n-3′ double-stranded repeats, followed by up to several hundred bases of a 3′ single-stranded G-rich overhang. The G-rich overhang is bound by the shelterin comp...

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Detalles Bibliográficos
Autores principales:	Smith, Emmanuel W., Lattmann, Simon, Liu, Zhehui Barry, Ahsan, Bilal, Rhodes, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853558/ https://www.ncbi.nlm.nih.gov/pubmed/35176105 http://dx.doi.org/10.1371/journal.pone.0264073

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