Synthesis, computational studies, tyrosinase inhibitory kinetics and antimelanogenic activity of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivatives

The over expression of melanogenic enzymes like tyrosinase caused many hyperpigmentaion disorders. The present work describes the synthesis of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivatives 3a–e and 5a–e as antimelanogenic agents. The tyrosinase inhibitory activity of synthesiz...

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Detalles Bibliográficos
Autores principales: Rafiq, Muhammad, Nazir, Yasir, Ashraf, Zaman, Rafique, Hummera, Afzal, Samina, Mumtaz, Amara, Hassan, Mubashir, Ali, Anser, Afzal, Khurram, Yousuf, Muhammad Rizwan, Saleem, Muhammad, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853709/
https://www.ncbi.nlm.nih.gov/pubmed/31456445
http://dx.doi.org/10.1080/14756366.2019.1654468

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