Cargando…
miR-488-3p Protects Cardiomyocytes against Doxorubicin-Induced Cardiotoxicity by Inhibiting CyclinG1
OBJECTIVE: To investigate the protective effects and regulatory mechanism of miR-488-3p on doxorubicin-induced cardiotoxicity. METHODS: The C57BL/6 mice and primary cardiomyocytes were used to construct doxorubicin-induced cardiomyocyte injury models in vivo and in vitro. The levels of miR-488-3p an...
Autores principales: | Yan, Mingjing, Cao, Yuan, Wang, Que, Xu, Kun, Dou, Lin, Huang, Xiuqing, Chen, Beidong, Tang, Weiqing, Lan, Ming, Liu, Bing, Zhu, Kaiyi, Yang, Yao, Sun, Shenghui, Zhang, Xiyue, Man, Yong, Hei, Mingyan, Shen, Tao, Li, Jian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853758/ https://www.ncbi.nlm.nih.gov/pubmed/35186188 http://dx.doi.org/10.1155/2022/5184135 |
Ejemplares similares
-
Dexrazoxane Protects Cardiomyocyte from Doxorubicin-Induced Apoptosis by Modulating miR-17-5p
por: Yu, Xiaoxue, et al.
Publicado: (2020) -
Astragalus polysaccharide restores autophagic flux and improves cardiomyocyte function in doxorubicin-induced cardiotoxicity
por: Cao, Yuan, et al.
Publicado: (2016) -
GCN2 deficiency ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and myocardial oxidative stress
por: Wang, Yue, et al.
Publicado: (2018) -
Cardiomyocyte Atrophy, an Underestimated Contributor in Doxorubicin-Induced Cardiotoxicity
por: Chen, De-Shu, et al.
Publicado: (2022) -
miR-154-5p Functions as an Important Regulator of Angiotensin II-Mediated Heart Remodeling
por: Wang, Que, et al.
Publicado: (2019)