Cargando…

Effect of Shenfu Injection on Differentiation of Bone Marrow Mesenchymal Stem Cells into Pacemaker-Like Cells and Improvement of Pacing Function of Sinoatrial Node

Sick sinus syndrome (SSS), a complex type of cardiac arrhythmia, is a major health threat to humans. Shenfu injection (SFI), a formula of traditional Chinese medicine (TCM), is effective in improving bradyarrhythmia. However, the underlying mechanism of SFI's therapeutic effect is subject to fe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Qi, Kang, Liang, Li, Yihua, Lin, Zina, Chu, Qingmin, Cai, Yinhe, Wu, Wei, Wang, Song, Qing, Lijin, Zhao, Xinjun, Li, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853776/ https://www.ncbi.nlm.nih.gov/pubmed/35186186 http://dx.doi.org/10.1155/2022/4299892

Ejemplares similares

Shenfu Injection: A Famous Chinese Prescription That Promotes HCN4 Activity in Bone Marrow Mesenchymal Stem Cells
por: Zhao, Xinjun, et al.
Publicado: (2021)

Sinoatrial node pacemaker cells: cardiomyocyte- or neuron-like cells?
por: Zhou, Bin
Publicado: (2021)

Pacemaker Synchronization of Electrically Coupled Rabbit Sinoatrial Node Cells
por: Verheijck, E. Etienne, et al.
Publicado: (1998)

Sinoatrial node pacemaker cells share dominant biological properties with glutamatergic neurons
por: Liang, Dandan, et al.
Publicado: (2021)

The end effector of circadian heart rate variation: the sinoatrial node pacemaker cell
por: Yaniv, Yael, et al.
Publicado: (2015)

Transcriptional and Epigenetic Landscape of Cardiac Pacemaker Cells: Insights Into Cellular Specialization in the Sinoatrial Node
por: Mandla, Ravi, et al.
Publicado: (2021)

Genetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous Pole
por: Ye, Wenduo, et al.
Publicado: (2015)

Pregnancy and oestrogen regulate sinoatrial node calcium homeostasis and accelerate pacemaking
por: El Khoury, Nabil, et al.
Publicado: (2018)

Assembly of the Cardiac Pacemaking Complex: Electrogenic Principles of Sinoatrial Node Morphogenesis
por: Easterling, Marietta, et al.
Publicado: (2021)

Importance of Gradients in Membrane Properties and Electrical Coupling in Sinoatrial Node Pacing
por: Inada, Shin, et al.
Publicado: (2014)

The Effect of Astragaloside on Pacemaker Current and the Cytoskeleton in Rabbit Sinoatrial Node Cells Under the Ischemia and Reperfusion Condition
por: Liu, Ruxiu, et al.
Publicado: (2018)

Hyperpolarization-Activated Current, I (f), in Mathematical Models of Rabbit Sinoatrial Node Pacemaker Cells
por: Verkerk, Arie O., et al.
Publicado: (2013)

Drivers of Sinoatrial Node Automaticity in Zebrafish: Comparison With Mechanisms of Mammalian Pacemaker Function
por: Stoyek, Matthew R., et al.
Publicado: (2022)

Calcium Transient and Sodium-Calcium Exchange Current in Human versus Rabbit Sinoatrial Node Pacemaker Cells
por: Verkerk, Arie O., et al.
Publicado: (2013)

Intracellular Na(+) Modulates Pacemaking Activity in Murine Sinoatrial Node Myocytes: An In Silico Analysis
por: Morotti, Stefano, et al.
Publicado: (2021)

cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells
por: Fenske, Stefanie, et al.
Publicado: (2020)

Functional Heterogeneity of Cell Populations Increases Robustness of Pacemaker Function in a Numerical Model of the Sinoatrial Node Tissue
por: Maltsev, Alexander V., et al.
Publicado: (2022)

Complete Atrial-Specific Knockout of Sodium-Calcium Exchange Eliminates Sinoatrial Node Pacemaker Activity
por: Groenke, Sabine, et al.
Publicado: (2013)

Cyclic AMP reverses the effects of aging on pacemaker activity and I(f) in sinoatrial node myocytes
por: Sharpe, Emily J., et al.
Publicado: (2017)

HCN4 pacemaker channels attenuate the parasympathetic response and stabilize the spontaneous firing of the sinoatrial node
por: Kozasa, Yuko, et al.
Publicado: (2018)

Characterization of the pace-and-drive capacity of the human sinoatrial node: A 3D in silico study
por: Amsaleg, Antoine, et al.
Publicado: (2022)

Pacemaker Activity of the Human Sinoatrial Node: An Update on the Effects of Mutations in HCN4 on the Hyperpolarization-Activated Current
por: Verkerk, Arie O., et al.
Publicado: (2015)

Role of sinoatrial node architecture in maintaining a balanced source-sink relationship and synchronous cardiac pacemaking
por: Unudurthi, Sathya D., et al.
Publicado: (2014)

Coupling and heterogeneity modulate pacemaking capability in healthy and diseased two-dimensional sinoatrial node tissue models
por: Campana, Chiara, et al.
Publicado: (2022)

Telocytes in the human sinoatrial node
por: Mitrofanova, Lubov B., et al.
Publicado: (2017)

Effects of muscarinic receptor stimulation on Ca(2+) transient, cAMP production and pacemaker frequency of rabbit sinoatrial node cells
por: van Borren, Marcel M. G. J., et al.
Publicado: (2009)

Is sodium current present in human sinoatrial node cells?
por: Verkerk, Arie O., et al.
Publicado: (2009)

Biochemical and biomechanical properties of the pacemaking sinoatrial node extracellular matrix are distinct from contractile left ventricular matrix
por: Gluck, Jessica M., et al.
Publicado: (2017)

Mechanistic Insights Into the Reduced Pacemaking Rate of the Rabbit Sinoatrial Node During Postnatal Development: A Simulation Study
por: Alghamdi, Azzah M., et al.
Publicado: (2020)

Cellular and Molecular Mechanisms of Functional Hierarchy of Pacemaker Clusters in the Sinoatrial Node: New Insights into Sick Sinus Syndrome
por: Lang, Di, et al.
Publicado: (2021)

Human Sinoatrial Node Pacemaker Activity: Role of the Slow Component of the Delayed Rectifier K(+) Current, I(Ks)
por: Verkerk, Arie O., et al.
Publicado: (2023)

Function and Dysfunction of Human Sinoatrial Node
por: Joung, Boyoung, et al.
Publicado: (2015)

Genetic Complexity of Sinoatrial Node Dysfunction
por: Wallace, Michael J., et al.
Publicado: (2021)

Lithium-Induced Sinoatrial Node Dysfunction
por: Sarangi, Ashish, et al.
Publicado: (2021)

Shenfu injection attenuates cardiac dysfunction and inhibits apoptosis in septic mice
por: Zhao, Liyun, et al.
Publicado: (2022)

Deciphering cellular signals in adult mouse sinoatrial node cells
por: Reddy, Gopireddy R., et al.
Publicado: (2021)

Pharmacokinetic evaluation of Shenfu Injection in beagle dogs after intravenous drip administration
por: Zhang, Yuqiao, et al.
Publicado: (2016)

The Calcium and Voltage Clocks in Sinoatrial Node Automaticity
por: Joung, Boyoung, et al.
Publicado: (2009)

CaMKII in sinoatrial node physiology and dysfunction
por: Wu, Yuejin, et al.
Publicado: (2014)

Sinoatrial Node Disease in Adults with Down’s Syndrome.
por: Kennedy, J, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9954ifv66le0ru6v71e41q275s