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T Lymphocyte Infiltration in Association with IDO1 Expression in Resected Lung Adenocarcinoma and Normal Adjacent Lung Tissues

BACKGROUND: Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the first step of tryptophan catabolism in the kynurenine (Kyn) pathway. IDO1 downregulates natural killer cell receptors, and by mechanism, tumor cells escape immune surveillance. METHODS: IDO1 protein and mRNA were assessed by immunohistoc...

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Detalles Bibliográficos
Autores principales:	Zhao, Xiaoling, Li, Yaran, Yang, Xu, Zhang, Xiaochong, Xie, Jing, Li, Shaoteng, Liu, Hongzhen, Guo, Jun, He, Lili, Chen, Wei, Liu, Dengxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853784/ https://www.ncbi.nlm.nih.gov/pubmed/35187162 http://dx.doi.org/10.1155/2022/2381018

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