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Hypoxia Tumor Microenvironment Activates GLI2 through HIF-1α and TGF-β2 to Promote Chemotherapy Resistance of Colorectal Cancer

BACKGROUND: A majority of relapse cases have been reported in colorectal cancer patients due to cancer stem cell progenitors. The factors responsible for chemoresistance have yet to be discovered and investigated as CSCs have reported escaping from chemotherapy's killing action. OBJECTIVE: In t...

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Detalles Bibliográficos
Autores principales:	Huang, Kun, Zhang, Xin, Hao, Yanhui, Feng, Ruixing, Wang, Haojie, Shu, Zhiwan, Li, An, Du, Minghu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853797/ https://www.ncbi.nlm.nih.gov/pubmed/35186110 http://dx.doi.org/10.1155/2022/2032895

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