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Vestibular Aqueduct Morphology and Meniere's Disease—Development of the “Vestibular Aqueduct Score” by 3D Analysis

Improved radiological examinations with newly developed 3D models may increase understanding of Meniere's disease (MD). The morphology and course of the vestibular aqueduct (VA) in the temporal bone might be related to the severity of MD. The presented study explored, if the VA of MD and non-MD...

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Autores principales: Noyalet, Laurent, Ilgen, Lukas, Bürklein, Miriam, Shehata-Dieler, Wafaa, Taeger, Johannes, Hagen, Rudolf, Neun, Tilmann, Zabler, Simon, Althoff, Daniel, Rak, Kristen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854222/
https://www.ncbi.nlm.nih.gov/pubmed/35187054
http://dx.doi.org/10.3389/fsurg.2022.747517
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author Noyalet, Laurent
Ilgen, Lukas
Bürklein, Miriam
Shehata-Dieler, Wafaa
Taeger, Johannes
Hagen, Rudolf
Neun, Tilmann
Zabler, Simon
Althoff, Daniel
Rak, Kristen
author_facet Noyalet, Laurent
Ilgen, Lukas
Bürklein, Miriam
Shehata-Dieler, Wafaa
Taeger, Johannes
Hagen, Rudolf
Neun, Tilmann
Zabler, Simon
Althoff, Daniel
Rak, Kristen
author_sort Noyalet, Laurent
collection PubMed
description Improved radiological examinations with newly developed 3D models may increase understanding of Meniere's disease (MD). The morphology and course of the vestibular aqueduct (VA) in the temporal bone might be related to the severity of MD. The presented study explored, if the VA of MD and non-MD patients can be grouped relative to its angle to the semicircular canals (SCC) and length using a 3D model. Scans of temporal bone specimens (TBS) were performed using micro-CT and micro flat panel volume computed tomography (mfpVCT). Furthermore, scans were carried out in patients and TBS by computed tomography (CT). The angle between the VA and the three SCC, as well as the length of the VA were measured. From these data, a 3D model was constructed to develop the vestibular aqueduct score (VAS). Using different imaging modalities it was demonstrated that angle measurements of the VA are reliable and can be effectively used for detailed diagnostic investigation. To test the clinical relevance, the VAS was applied on MD and on non-MD patients. Length and angle values from MD patients differed from non-MD patients. In MD patients, significantly higher numbers of VAs could be assigned to a distinct group of the VAS. In addition, it was tested, whether the outcome of a treatment option for MD can be correlated to the VAS.
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spelling pubmed-88542222022-02-19 Vestibular Aqueduct Morphology and Meniere's Disease—Development of the “Vestibular Aqueduct Score” by 3D Analysis Noyalet, Laurent Ilgen, Lukas Bürklein, Miriam Shehata-Dieler, Wafaa Taeger, Johannes Hagen, Rudolf Neun, Tilmann Zabler, Simon Althoff, Daniel Rak, Kristen Front Surg Surgery Improved radiological examinations with newly developed 3D models may increase understanding of Meniere's disease (MD). The morphology and course of the vestibular aqueduct (VA) in the temporal bone might be related to the severity of MD. The presented study explored, if the VA of MD and non-MD patients can be grouped relative to its angle to the semicircular canals (SCC) and length using a 3D model. Scans of temporal bone specimens (TBS) were performed using micro-CT and micro flat panel volume computed tomography (mfpVCT). Furthermore, scans were carried out in patients and TBS by computed tomography (CT). The angle between the VA and the three SCC, as well as the length of the VA were measured. From these data, a 3D model was constructed to develop the vestibular aqueduct score (VAS). Using different imaging modalities it was demonstrated that angle measurements of the VA are reliable and can be effectively used for detailed diagnostic investigation. To test the clinical relevance, the VAS was applied on MD and on non-MD patients. Length and angle values from MD patients differed from non-MD patients. In MD patients, significantly higher numbers of VAs could be assigned to a distinct group of the VAS. In addition, it was tested, whether the outcome of a treatment option for MD can be correlated to the VAS. Frontiers Media S.A. 2022-02-04 /pmc/articles/PMC8854222/ /pubmed/35187054 http://dx.doi.org/10.3389/fsurg.2022.747517 Text en Copyright © 2022 Noyalet, Ilgen, Bürklein, Shehata-Dieler, Taeger, Hagen, Neun, Zabler, Althoff and Rak. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Noyalet, Laurent
Ilgen, Lukas
Bürklein, Miriam
Shehata-Dieler, Wafaa
Taeger, Johannes
Hagen, Rudolf
Neun, Tilmann
Zabler, Simon
Althoff, Daniel
Rak, Kristen
Vestibular Aqueduct Morphology and Meniere's Disease—Development of the “Vestibular Aqueduct Score” by 3D Analysis
title Vestibular Aqueduct Morphology and Meniere's Disease—Development of the “Vestibular Aqueduct Score” by 3D Analysis
title_full Vestibular Aqueduct Morphology and Meniere's Disease—Development of the “Vestibular Aqueduct Score” by 3D Analysis
title_fullStr Vestibular Aqueduct Morphology and Meniere's Disease—Development of the “Vestibular Aqueduct Score” by 3D Analysis
title_full_unstemmed Vestibular Aqueduct Morphology and Meniere's Disease—Development of the “Vestibular Aqueduct Score” by 3D Analysis
title_short Vestibular Aqueduct Morphology and Meniere's Disease—Development of the “Vestibular Aqueduct Score” by 3D Analysis
title_sort vestibular aqueduct morphology and meniere's disease—development of the “vestibular aqueduct score” by 3d analysis
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854222/
https://www.ncbi.nlm.nih.gov/pubmed/35187054
http://dx.doi.org/10.3389/fsurg.2022.747517
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