BCG-induced trained immunity enhances acellular pertussis vaccination responses in an explorative randomized clinical trial

Acellular pertussis (aP) booster vaccines are central to pertussis immunization programs, although their effectiveness varies. The Bacille Calmette-Guérin (BCG) vaccine is a prototype inducer of trained immunity, which enhances immune responses to subsequent infections or vaccinations. While previou...

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Detalles Bibliográficos
Autores principales: Gillard, Joshua, Blok, Bastiaan A., Garza, Daniel R., Venkatasubramanian, Prashanna Balaji, Simonetti, Elles, Eleveld, Marc J., Berbers, Guy A. M., van Gageldonk, Pieter G. M., Joosten, Irma, de Groot, Ronald, de Bree, L. Charlotte J., van Crevel, Reinout, de Jonge, Marien I., Huynen, Martijn A., Netea, Mihai G., Diavatopoulos, Dimitri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854388/
https://www.ncbi.nlm.nih.gov/pubmed/35177621
http://dx.doi.org/10.1038/s41541-022-00438-4

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