Cell adhesion molecule KIRREL1 is a feedback regulator of Hippo signaling recruiting SAV1 to cell-cell contact sites

The Hippo/YAP pathway controls cell proliferation through sensing physical and spatial organization of cells. How cell-cell contact is sensed by Hippo signaling is poorly understood. Here, we identified the cell adhesion molecule KIRREL1 as an upstream positive regulator of the mammalian Hippo pathw...

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Detalles Bibliográficos
Autores principales: Paul, Atanu, Annunziato, Stefano, Lu, Bo, Sun, Tianliang, Evrova, Olivera, Planas-Paz, Lara, Orsini, Vanessa, Terracciano, Luigi M., Charlat, Olga, Loureiro, Zinger Yang, Ji, Lei, Zamponi, Raffaella, Sigoillot, Frederic, Lei, Hong, Lindeman, Alicia, Russ, Carsten, Reece-Hoyes, John S., Nicholson, Thomas B., Tchorz, Jan S., Cong, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854406/
https://www.ncbi.nlm.nih.gov/pubmed/35177623
http://dx.doi.org/10.1038/s41467-022-28567-3

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