A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit

Many cellular processes, including ribosome biogenesis, are regulated through post-transcriptional RNA modifications. Here, a genome-wide analysis of the human mitochondrial transcriptome shows that 2’-O-methylation is limited to residues of the mitoribosomal large subunit (mtLSU) 16S mt-rRNA, intro...

Descripción completa

Detalles Bibliográficos
Autores principales: Rebelo-Guiomar, Pedro, Pellegrino, Simone, Dent, Kyle C., Sas-Chen, Aldema, Miller-Fleming, Leonor, Garone, Caterina, Van Haute, Lindsey, Rogan, Jack F., Dinan, Adam, Firth, Andrew E., Andrews, Byron, Whitworth, Alexander J., Schwartz, Schraga, Warren, Alan J., Minczuk, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854578/
https://www.ncbi.nlm.nih.gov/pubmed/35177605
http://dx.doi.org/10.1038/s41467-022-28503-5

Ejemplares similares

Ejemplares similares