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BrewerIX enables allelic expression analysis of imprinted and X-linked genes from bulk and single-cell transcriptomes

Genomic imprinting and X chromosome inactivation (XCI) are two prototypical epigenetic mechanisms whereby a set of genes is expressed mono-allelically in order to fine-tune their expression levels. Defects in genomic imprinting have been observed in several neurodevelopmental disorders, in a wide ra...

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Detalles Bibliográficos
Autores principales:	Martini, Paolo, Sales, Gabriele, Diamante, Linda, Perrera, Valentina, Colantuono, Chiara, Riccardo, Sara, Cacchiarelli, Davide, Romualdi, Chiara, Martello, Graziano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854590/ https://www.ncbi.nlm.nih.gov/pubmed/35177756 http://dx.doi.org/10.1038/s42003-022-03087-4

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